Juvenile Systemic Lupus Erythematosus (JSLE) is more commonly referred to as Lupus or Childhood Lupus. This is a life long disease in children which can cause inflammation in any part of the body including skin, joints and many of the body’s major organs. Lupus is an autoimmune disease, which means the body’s immune system attacks healthy tissues, but why this happens is not fully understood. There is no cure for Lupus but there are many effective treatments and new developments in care.